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P.E.A. (palmitoylethanolamide) is a molecule that is naturally present in all tissues of the body. It acts through the body’s endocannabinoid system to support temporary aches and pains. Technically classified as a lipid mediator, PEA works by indirectly activating cannabinoid receptors. Cannabinoid receptors work through the endocannabinoid system to help maintain balance throughout the body and help regulate many processes, including cellular metabolism and immune modulation, making PEA a standout molecule for supporting overall wellness and healthy aging.*

Typically, PEA supplements have poor bioavailability. That's why ProHealth’s PEA utilizes micronized technology to ensure optimal absorption and maximum bioavailability in your body.

Benefits:

Protects cells from injury and everyday stress*
Supports a healthy inflammatory response*
Temporary relief from minor pain due to overexertion*
Supports healthy aging and longevity*
May support a good night's rest*

Supports cellular repair and a healthy inflammatory response.* The body produces PEA to protect cells from injury. PEA levels may decline during imbalanced states. Supplementation with PEA is thought to “top-up” levels in the body to restore balance and overall homeostasis.¹In addition, PEA acts on PPAR-alpha and TRPV1 receptors, indirectly helping support CB1 and CB2 endocannabinoid receptors. It also helps support the activity of COX, eNOS, and iNOS, three enzymes important for a balanced immune response and overall, whole-body function.*

Temporary relief from minor pain due to overexertion.* Data from clinical trials involving over 1,000 participants found that PEA may support the body’s response to mild, temporary pain.² In a randomized, double-blind, placebo-controlled crossover study, 14 healthy volunteers were exposed to a pain model. Supplementation with 1200 mg PEA reduced physical discomfort by more than 20% when compared with placebo.*³

Supports healthy aging and longevity.* In preclinical studies, PEA helped support intercellular communication pathways associated with aging. It may also assist in the maintenance of certain stem cells and potentially help support antioxidative status and mitochondrial function.*

May support a good night’s rest.* PEA may help improve sleep quality through the regulation of anandamide (AEA). AEA is an endocannabinoid that can help support signaling during NREM (non-rapid eye movement) sleep. It also helps activate TRPV1, which helps with the relaxation of blood vessels.*¹

\nReferences:\n

1. Clayton P et al. Int J Mol Sci. 2021;22(10):5305.
2. Artukoglu BB et al. Pain Physician. 2017;(20):353-362.
3. Lang-Illievich K et al. Nutrients. 2022;14(19):4084.

Indirectly acts on both CB1 and CB2 cannabinoid receptors in the endocannabinoid pathway*
Activates PPAR-alpha, a key regulator of energy and immune balance*
Micronized technology supports superior absorption

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Supplement Facts
Serving Size: 1 Capsule \n
Servings Per Container: 120 \n
Amount Per Serving	%DV
Micronized Palmitoylethanolamide (PEA) \n	300 mg \n	† \n
† Daily Value (DV) not established

REV.06.24

\nOTHER INGREDIENTS: Vegetable capsule, rice flour.
\nDOES NOT CONTAIN: Dairy, egg, soy, wheat, gluten, fish, shellfish, tree nuts, peanuts, sesame.
\nSUGGESTED DAILY USE: Take (1) one capsule, 1 to 4 times daily, or as directed by your healthcare professional.
\nNOTE: Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. KEEP OUT OF REACH OF CHILDREN.
\n
\nCAUTION: Not intended for use if you are pregnant or nursing. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product.
\n

\nScience-First Formulations: We source only the highest quality ingredients backed by validated research to help you achieve your longevity goals.
\nQuality Manufacturing Practices. All of our products are manufactured in a FDA-registered, GMP-certified facility.
\nThird-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.

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Pure Micronized P.E.A. - 300 mg, 120 capsules

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