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In today's fast-paced world, achieving optimal health often feels like a challenge. The Prolon^® 5-Day Fasting Nutrition Program offers a scientifically-backed solution that simplifies your journey. Designed by Dr. Valter Longo, a leading expert in longevity and gerontology, this innovative program combines the benefits of fasting with the nourishment your body needs to thrive. Through a carefully curated selection of plant-based foods, Prolon^® activates your body’s natural fasting mode, promoting cellular rejuvenation, enhanced metabolism, and a balanced emotional state—all without the stress of traditional fasting. Whether you seek to boost your vitality, support healthy aging, or kickstart a new wellness routine, Prolon^® provides a transformative experience in just five days.

Product highlights

Designed to mimic the benefits of intermittent fasting (IF) or prolonged water fasting
Discovered and developed at the Longevity Institute of the University of Southern California
Over 20 years and $36 million invested in research & development
Scientifically tested by 18 global universities
Clinically proven outcomes
Long-term, lasting results

Studied health benefits

Fasting Mimicking Diets (FMDs) like Prolon^® have been studied extensively in clinical research for years. One study reported a reduction in biological age by approximately 2.5 years.¹ Other studies have shown improvements in:

Systemic health
Hallmarks of aging, including cellular senescence and autophagy
Body composition, ketogenesis, and fat burning
Blood sugar markers
Cognitive performance, memory, and learning
Energy, clarity, and well-being
Skin hydration and glow^1-6\n

What's in the meal kit?

This kit contains a 5-day supply of the Prolon^® Fasting Nutrition Program. Eat and drink the food as instructed for five continuous days. No other food should be consumed during the 5-day period. Unlimited amounts of water and herbal teas are allowed.

Prolon^® is a 5-day meal program providing about 1150 calories on Day 1 and approximately 800 calories on Days 2-5. Studies show that a very low-calorie diet (VLCD) of 800 calories per day can mimic important aspects of fasting and may offer similar benefits.

Prolon^® consists of proprietary plant-based soups, bars, drinks, snacks, teas and supplements – all designed to maximize the protective effects related to fasting, while providing micronutrient nourishment and minimizing hunger and the burdens of fasting. The program covers a period of five continuous days.

Fasting diets like Prolon^® activate autophagy, a natural process where cells break down and eliminate old proteins and other unwanted substances. During periods of reduced nutrient intake, these breakdown products are repurposed as fuel, helping to sustain the body and in the process promote cellular renewal.

Fasting diets like Prolon^® primarily support three key nutrient-sensing pathways: IGF-1, mTOR, and PKA. PKA responds mainly to sugars and carbohydrates, IGF-1 to protein (especially animal protein), and mTOR to IGF-1 and amino acids. These pathways interact to support cell growth and initiate a stress-resistant fasting state.

Considerations

The Prolon^® meal kit contains products with soy, nuts, celery, oats, and sesame and should not be used if you have allergies to any of these ingredients.

Although fasting is safe for most people, you should talk to your healthcare provider before beginning any diet or diet program to ensure it is safe and right for you.

If you are underweight, have an eating disorder, have a pre-existing health condition or are taking any prescription medications, consult your healthcare provider before starting a fast.

It’s best to avoid strenuous exercise during the 5-day program.

References:

1. Brandhorst S et al. Nat Commun. 2024;15(1):1309.
2. Wei M et al. Sci Transl Med. 2017;9(377).
3. Brandhorst S et al. Cell Metab. 2015;22(1):86-99.
4. Choi IY et al. Cell Rep. 2016;15(10):2136-2146.
5. Rangan P et al. Cell Rep. 2022;40(13):111417.
6. Mishra A et al. Nat Metab. 2021;3(10):1342-1356.

\nSoups: Minestrone, Tomato, Chickpea & Leeks, Carrot Ginger, Red Bell Pepper & Onion, Lentil Curry, and Green Pea & Chives.

Fasting Bars: Nuts & Honey, Chocolate Chip, and Coconut Macadamia.

Fasting Shake: Vanilla.

Snacks: L-Bar (proprietary nut-based bar), L-Bar (proprietary choco crisp bar), Kale Crackers, Almond & Kale Crackers, Olives with Herbs, and Olives with Sea Salt.

Drinks: L-Drink (tropical berry flavor), L-Drink (orange flavor), Herbal Teas (hibiscus, spearmint, spearmint lemon).

Supplements: NR-1 (vegetable powder with vitamins & minerals supplement), Algal Oil, and Extra Virgin Olive Oil.

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Prolon® 5-Day Fasting Nutrition Program

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